THE DEFINITIVE GUIDE TO TRAMADOL (RETARD)

Opioid exercise is because of equally low affinity binding of the dad or mum compound and better affinity binding from the O-demethylated metabolite M1 to μ-opioid receptors. In animal products, M1 is as many as 6 situations far more strong than tramadol in manufacturing analgesia and 200 occasions much more strong in μ-opioid binding.Use the low